Comparison of taurocholate accumulation in cultured hepatocytes of pig, rat and man
โ Scribed by Jaap Kwekkeboom; Hans M.G. Princen; Eline M. van Voorthuizen; Piet Meijer; Herman Jan M. Kempen
- Book ID
- 115762356
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 450 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
Taurocholate (TC) uptake by adult rat hepatocytes co-cultured with other rat liver epithelial cells (RLEC) was studied comparatively to hepatocytes in primary culture. Cells were cultured on Petri dishes for desired times prior to measuring their ability to transport TC. TC uptake was linear for 150
Previous studies have demonstrated marked differences in the capacity of hepatocytes from rats or hamsters to mediate the metabolic activation of chemical carcinogens to genotoxic (ie, mutagenic) products. Thus far, very few investigations of species differences in DNA repair have been performed. Th