Amide proton exchange rates of oxidized
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Jennifer L. Marmorino; Douglas S. Auld; Stephen F. Betz; Donald F. Doyle; Gregor
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Article
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1993
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Cold Spring Harbor Laboratory Press
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English
β 979 KB
## Abstract Proton NMR spectroscopy was used to determine the rate constant, __k~obs~__, for exchange of labile protons in both oxidized (Fe(III)) and reduced (Fe(II)) isoβ1βcytochrome __c.__ We find that slowly exchanging backbone amide protons tend to lack solventβaccessible surface area, possess