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Comparison of receptor binding, biological activity, and in vivo tracer kinetics for 1,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D2, and its 24 epimer

โœ Scribed by T.A. Reinhardt; C.F. Ramberg; R.L. Horst


Book ID
115708057
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
777 KB
Volume
273
Category
Article
ISSN
0003-9861

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The steroid hormone Ia,25-dihydroxyvitamin D3 has been shown to exert rapid effects (1 5 s to 5 min) in osteoblasts. These effects occur in osteoblast-like cells lacking the nuclear vitamin D receptor, ROS 24/1, suggesting that a separate signalling system mediates the rapid actions. These non-genom