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Comparison of protein phosphorylation induced by mitogen and phorbol diester stimulation of murine T and B lymphocytes

✍ Scribed by John G. Monroe; Glen N. Gaulton


Book ID
112936872
Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
649 KB
Volume
4
Category
Article
ISSN
0257-277X

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The effect of sodium orthovanadate on enhancement of DNA synthesis by T and B cell mitogenic agents was studied using murine thymocytes and splenocytes. Addition of vanadate to thymocyte cultures inhibited the mitogenic response induced by concanavalin A in a dose dependent manner (50% inhibition at