Stimulation of murine B lymphocytes to IgG synthesis and secretion by the mitogens lipopolysaccharide and lipoprotein and its inhibition by anti-immunoglobulin antibodies

Polyclonal activation of the murine immu

Polyclonal activation of the murine immune system by an antibody to IgD. VI. Influence of doses of goat anti-mouse δ chain and normal goat IgG on B lymphocyte proliferation and differentiation

✍ Fred D. Finkelman; Joanne Smith; Nelly Villacreses; Eleanor S. Metcalf 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 726 KB

The injection of mice with 800 micrograms of an affinity-purified goat antibody to mouse IgD (GaM delta) induces early, T-independent polyclonal increases in the expression of B cell surface Ia, and B cell size and DNA synthesis, as well as later, T-dependent polyclonal increases in spleen cell numb