## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Comparison of Pgp- and MRP-Mediated Multidrug Resistance in Leukemia Cell Lines
β Scribed by Yu-Ping Gong; Ting Liu; Yong-Qian Jia; Li Qin; Cheng-Qi Deng; Ren-Yang Ou Yang
- Book ID
- 105675305
- Publisher
- Carden Jennings Publishing
- Year
- 2002
- Tongue
- English
- Weight
- 521 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0925-5710
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Annamycin (Ann) is a highly lipophilic anthracycline antibiotic that has been shown to circumvent MDR-1 both in vitro and in vivo. A liposomal formulation of Ann is currently in phase I clinical trials. The multidrug resistance-associated protein (MRP) has been found to be over-expressed in some hum
## Abstract Amooranin (AMR), a plant terpenoid, isolated from __Amoora rohituka__, was investigated for its ability to overcome multidrug resistance in human leukemia and colon carcinoma cell lines. AMR IC~50~ values of multidrugβresistant leukemia (CEM/VLB) and colon carcinoma (SW620/Adβ300) cell