Comparison of myeloablative and nonmyeloablative hematopoietic stem cell transplantation for treatment of chronic myeloid leukemia
β Scribed by Ming-Huang Chen; Tzeon-Jye Chiou; Peng-Chan Lin; Jyh-Pyng Gau; Hui-Chi Hsu; Liang-Tsai Hsiao; Jin-Hwang Liu; Po-Min Chen
- Publisher
- Carden Jennings Publishing
- Year
- 2007
- Tongue
- English
- Weight
- 99 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0925-5710
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## Abstract Chronic Myeloid Leukemia (CML), a myeloproliferative disease of stem cell origin, is characterized by the presence of the Philadelphia (Ph) chromosome and the __bcrβabl__ oncogene. The BCRβABL fusion gene product, thought to be causative in CML, has multiple effects on diverse cell func
## Background: The objective of this analysis was to evaluate the role of autologous stem cell transplantation (asct) in prolonging disease free survival (dfs) and overall survival (os) in patients with chronic myeloid leukemia (cml) who received autografts of philadelphia chromosome (ph) positive