Comparison of multiple in vivo and in vitro parameters in untreated patients with Hodgkin's disease
β Scribed by Delvyn C. Case Jr.; John A. Hansen; Charles W. Young; Bo Dupont; Carl M. Pinsky; Robert A. Good
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 710 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0008-543X
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Non-caseating sarcoid-like epithelioid granulomas associated with Hodgkin's disease have been found in 55 patients initially staged and treated at the Stanford University School of Medicine. These patients are compared to 553 concurrent patients not having granulomas associated with their Hodgkin's
Peripheral blood lymphocytes from six untreated patients with Hodgkin's disease were exposed to various doses of ionizing radiation in vitro and thereafter tested for reactivity to PHA and ConA using DNA synthesis as a marker of viability. While the responsiveness of Hodgkin's disease lymphocytes wa