✦ LIBER ✦

Comparison of mianserin and dothiepin treatment on the serotonergic system in depressed patients

✍ Scribed by J. Butler; B. E. Leonard

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 342 KB
Volume: 5
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470050410

No coin nor oath required. For personal study only.

✦ Synopsis

Depressed patients showed a decreased 5-HT uptake rate and aggregation response and increased platelet ketanserin binding, compared to normal controls. Five weeks treatment with either mianserin or dothiepin improved the biochemical parameters in the patients, although the parameters still had not returned to control levels. There was no ditrerence between the biochemical markers in the mianserin and dothiepin groups at any time during the study.

📜 SIMILAR VOLUMES

The Effect of Paroxetine and Dothiepin o

The Effect of Paroxetine and Dothiepin on Subjective Sleep in Depressed Patients

✍ JOHN S. KERR; DIANE B. FAIRWEATHER; IAN HINDMARCH 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 75 KB 👁 2 views

Paroxetine improve the quality of sleep and the ease of waking up on subjective measures of sleep (the LSEQ). Dothiepin in contrast improved the ease of getting to sleep, but caused a reduced quality of sleep and a `hangover' eect the next morning.

The effects of fluoxetine and dothiepin

The effects of fluoxetine and dothiepin on cognitive function in depressed patients in general practice

✍ D. B. Fairweather; N. Stanley; J. S. Yoon; I. Hindmarch 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 177 KB 👁 2 views

The objective of this study was to assess whether there are any dierences between ¯uoxetine and dothiepin on cognitive function of patients with major depression (DSMIII-R). A randomized, double-blind, parallel group design, 6 week trial in patients in general practice was employed where patients we

Controlled Comparison of Tianeptine, Alp

Controlled Comparison of Tianeptine, Alprazolam and Mianserin in the Treatment of Adjustment Disorders with Anxiety and Depression

✍ MARC ANSSEAU; MICHEL BATAILLE; GUY BRIOLE; ANDRÉ DE NAYER; PIERRE ANDRÉ FAUCHÈRE 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 439 KB 👁 2 views

A multicentre study compared tianeptine (37.5 mg/day), an original psychotropic compound characterized by both antidepressant and anxiolytic potentials, with a reference antidepressant, mianserin (60 mgkday) and a reference anxiolytic, alprazolam (1.5 mglday), in the treatment of 152 patients fulfil

Serotonergic drugs in the treatment of d

Serotonergic drugs in the treatment of depressive and anxiety disorders

✍ Johan A. Den Boer; Fokko J. Bosker; Bernhard R. Slaap 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 3 views

Role of serotonergic and noradrenergic s

Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders

✍ Kerry J. Ressler; Charles B. Nemeroff 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB 👁 2 views

There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent wi

The effect of treatment with ketoconazol

The effect of treatment with ketoconazole on central CRH systems of depressed patients

✍ Georgios Paslakis; Olivera Lecei; Günther K. Stalla; Rainer Landgraf; Manfred Uh 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## Abstract ## Objectives Steroid‐synthesis inhibitors are reported to reduce psychopathology in treatment‐resistant depressed patients. ## Methods We studied the effect of a 3‐week treatment with ketoconazole on the evening plasma concentrations of cortisol, corticosteroid‐binding globulin (CBG