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Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits

โœ Scribed by Su-Lan Hsiu; Tang-Yen Huang; Yu-Chi Hou; Der-Hang Chin; Pei-Dawn Lee Chao

Book ID
117173347
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
86 KB
Volume
70
Category
Article
ISSN
0024-3205

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โœ Hyoung J. Kim; Jun S. Choi ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 95 KB ๐Ÿ‘ 2 views

It was reported that verapamil is metabolized via hepatic microsomal cytochrome P450 (CYP) 3A4 and that naringin (a component of grapefruit juice) inhibits CYP3A4 in humans. Hence, after oral administration of verapamil, the total area under the plasma concentration-time curve from time zero to time