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COMPARISON OF METABOLIC ABNORMALITIES IN DIABETES MELLITUS INDUCED BY STREPTOZOTOCIN OR BY ALLOXAN

โœ Scribed by K.R.L. Mansford; Lionel Opie


Book ID
118221071
Publisher
The Lancet
Year
1968
Tongue
English
Weight
297 KB
Volume
291
Category
Article
ISSN
0140-6736

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The pharmacokinetic and pharmacodynamic parameters of torasemide were compared after intravenous administration at a dose of 2 mg/kg to diabetic rats induced by alloxan (DMIA) or streptozotocin (DMIS), and their respective control rats. It was reported that torasemide was mainly metabolized via CYP2