𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Comparison of helium and argon as collision gases in the high energy collision-induced decomposition of MH+ions of peptides

✍ Scribed by Jozsef Bordas-Nagy; Dominique Despeyroux; Keith R. Jennings

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
866 KB
Volume
3
Category
Article
ISSN
1044-0305

No coin nor oath required. For personal study only.

✦ Synopsis

Collision-induced decompositions (CID) of protonated peptides were studied using a four-sector mass spectrometer. The collision gases employed were helium and argon. The CID spectra of several peptides covering the molecular mass region of 905-2465 u were recorded. These investigations established several previously unrecognized differences between the CID spectra obtained with helium and argon as collision gases. These can be summarized as follows: (1) Structurally significant and specific side chain fragmentations (dn (f), wn (f) and vn, ion types) are greatly reduced or completely missing in the CID spectra obtained with helium as a collision gas compared to those obtained with argon. (2) As the peptide molecular mass increases, argon, which is heavier than helium, is increasingly more efficient than helium for generating fragment ions.

πŸ“œ SIMILAR VOLUMES

Factors affecting immonium ion intensiti
Factors affecting immonium ion intensities in the high-energy collision-induced decomposition spectra of peptides
✍ T. Madden; K. J. Welham; M. A. Baldwin πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 347 KB

## Abstract Each amino acid in a peptide has a characteristic immonium ion (H~2~N^+^ο£ΎCHR), the presence of which in a mass spectrum can indicate the presence of that amino acid. High‐energy collision‐induced decomposition studies on small peptide ions formed by fast atom bombardment showed the rela

Comparison between collision induced dis
Comparison between collision induced dissociation of electrosprayed protonated peptides in the up-front source region and in a low-energy collision cell
✍ W. D. van Dongen; J. I. T. van Wijk; B. N. Green; W. Heerma; J. Haverkamp πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 2 views

A systematic comparison between the up-front Collision induced dissociation (CID) mass spectra and low-energy CID tandem mass spectra from twenty-one singly and/or doubly charged peptides has been made. CID spectra of the peptides were recorded at different electrode voltages in the up-front source