## Abstract The enhancement pattern of chemically induced hepatocellular carcinomas (HCCs) after intravenous administration of the hepatobiliary magnetic resonance (MR) contrast agent gadolinium‐EOB‐DTPA (ethoxybenzyl‐diethylenetriaminepentaacetic acid) was compared with the uptake pattern of techn
Comparison of Gd-DTPA and Tc99m-DTPA: Tissue efficacy versus distribution
✍ Scribed by K.R. Burnett; E.J. Goldstein; J. Hansell; G.L. Wolf; J. Dizon; D. Gelblum
- Book ID
- 103908552
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 133 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0730-725X
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Rat plasma distribution data obtained following IV administration of 99mTc(DTPA) alone or after co-administration of 99mTc(DTPA) and 153Gd-labeled Gd(DTPA)2- at 0.001, 0.1, and 1.0 mmol Gd/kg were evaluated using compartmental modeling techniques. A three-compartment open model was found to fit the
## Abstract A new hepatobiliary contrast agent for magnetic resonance (MR) imaging, gadolinium‐ethoxybenzy1 (EOB)‐diethylemetriaminepentaacetic acid (DTPA), was compared with Gd‐DTPA to define the potential for improving tumor‐liver contrast in a rodent liver adenocarcinoma model. With a T1‐weighte