Comparison of effects of HGF and EGF on cellular calcium in rat hepatocytes
β Scribed by Tetsuya Mine; Itaru Kojima; Etsuro Ogata; Toshikazu Nakamura
- Book ID
- 115764777
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 534 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
Adult rat hepatocytes were grown in serum-free medium containing 0.05-4 mM Ca++ and 40 ng/ml EGF. After 48 hours of cultivation the mitotic index and the percentage of second division metaphases were determined. The results demonstrated a maximum proliferation response to EGF at a Ca++ concentration
## Abstract Hepatocyte growth factor (HGF) also known as hepatopoietin A (HPTA) (Michalopoulos, FASEB J., 4:176β187, 1990) is a heparinβbinding growth factor whose characterization and tissue distribution have been reported elsewhere. This growth factor was recently cloned and its amino acid sequen