ThinPrep processing, an automated cytopreparatory method, has been reported to show good correlation with conventional preparations and to reduce the rate of false-negative diagnoses. In a retrospective review of 230 consecutive nongynecologic cytology cases, we compare the ThinPrep (TP) method with
Comparison of conventional and thinprep preparations of mucoid cytology samples
โ Scribed by K. Hees; P. B. Lebeau
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 373 KB
- Volume
- 12
- Category
- Article
- ISSN
- 8755-1039
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โฆ Synopsis
Cytologicalspecimens containing large amounts of mucus and/or blood are ofen a considerable problem as far as preparation and especially screening are concerned. The Thinprep''') -method, slides automatically, eliminates dSgiculties in both areas. Comparing ThinPreps to conventionally prepared samples reveals
smears each, were compared with a single slide per case prepared with the Thinprep Processor. Our objective was to establish whether these single slides from the newer ble to those of the conventional method. which uses a mucolYtic and hemobsing solution and Prepares procedure provide results that are qualitatively compara-~~ equivalent or even superior cellular preservation. Cells are spread in a thin layer, mostly with only a minimal amount of residual mucus or blood Screening is consequently much easier and faster, The time-saving effect does not compromise the diagnostic accuracy, as we could demonstrate with an 92% overall agreement in both procedures. The diyerence of 8% couldpossibly be attributed to inadequate splitting of the samples. Diagn Cytopathol 1995; 12:181-185.
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