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Comparison of checkpoint responses triggered by DNA polymerase inhibition versus DNA damaging agents

✍ Scribed by Jen-Sing Liu; Shu-Ru Kuo; Thomas Melendy

Book ID
113808235
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
264 KB
Volume
532
Category
Article
ISSN
0027-5107

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The polymerase inhibition assay: A metho
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✍ Gareth J. S. Jenkins; Brian Burlinson; James M. Parry πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 162 KB

We report here the development of the polymerase inhibition assay (PI assay), a methodology capable of simultaneously identifying multiple DNA-damaging agents. The PI assay was developed in order to fulfil a requirement for the screening of new pharmaceuticals for potential DNA-damaging effects. The