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Inhibition of hepatitis B DNA polymerase by intercalating agents

โœ Scribed by HIRSCHMAN, SHALOM Z.; GARFINKEL, ESTHER


Book ID
109708632
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
392 KB
Volume
271
Category
Article
ISSN
0028-0836

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Inhibition of human hepatitis B virus DN
โœ Pei-Zhen Tao; Bengt Lรถfgren; Desmond Lake-Bakaar; Nils Gunnar Johansson; Roelf D ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 605 KB

Replication of hepadnaviruses involves a viral DNA polymerase containing both a DNA-dependent and an RNA dependent activity. This polymerase is a potential target for chemotherapy against hepatitis B. We have used human hepatitis B virus DNA-dependent DNA polymerase from human serum and duck hepatit