Comparison of acute effects of anthracyclines on cardiac electrophysiological parameters of isolated guinea-pig hearts
β Scribed by Gerhard Stark; Ulrike Stark; Hellmut Samonigg; Katharina Kasparek; Andreas Lueger; Svila Nagl; Herwig Bertuch; Ernst Pilger; Helmut A. Tritthart
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 413 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0344-5704
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An extract obtained from the leaves of Ageratum conyzoides L. changed the electrocardiogram, atrial impulse velocity, and coronary vessels resistance on isolated guinea-pig heart. Electrocardiographic alterations were: (a) PR interval increased from 80 AE 1.4 ms to 105 AE 14 ms (p `0.01); (b) QT int
## Direct effects of platelet activating factor (PAF) on The direct effects of platelet activating factor (PAF) (2.5 nM) on isolated guinea pig heart were studied: first, on Langendorff model perfused hearts, using the radiolabelled microspheres technique, we found that PAF reduced the myocardial