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Comparison of 5-Fluorouracil Pharmacokinetics in Whole Blood, Plasma, and Red Blood Cells in Patients with Colorectal Cancer

✍ Scribed by Wiboon Wattanatorn; Howard L. McLeod; Fiona Macklon; Muriel Reid; Keith E. Kendle; James Cassidy


Book ID
112113704
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
518 KB
Volume
17
Category
Article
ISSN
0277-0008

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✍ K. -M. Chu; S. -M. Shieh; O. Y. -P. Hu πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 630 KB

The pharmacokinetics of enantiomers of pimobendan and their demethylated metabolites in plasma and red cells were studied in 8 normal healthy volunteers. After racemic pimobendan 5 mg IV, the plasma concentration-time curve followed a two-compartment open-model with elimination half-lives of 1.81 h