Comparing mechano-transduction in fibroblasts deficient of focal adhesion proteins
โ Scribed by Tuli Dey; Melanie C. Mann; Wolfgang H. Goldmann
- Book ID
- 116302322
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 772 KB
- Volume
- 413
- Category
- Article
- ISSN
- 0006-291X
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## Abstract We examined the consequences of vโCrk expression in mouse embryo fibroblasts deficient Src family kinases or p130CAS. We found that Src kinases are essential for p130CAS/vโCrk signaling leading to FAK phosphorylation and cell migration in which Src is likely to mediate the focal adhesio