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Comparing Experimental Designs for Benchmark Dose Calculations for Continuous Endpoints

โœ Scribed by Kristi Kuljus; Dietrich Von Rosen; Salomon Sand; Katarina Victorin


Book ID
109157545
Publisher
Springer
Year
2006
Tongue
English
Weight
328 KB
Volume
26
Category
Article
ISSN
1573-9147

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## Abstract We introduce a new optimal design for dose finding with a continuous efficacy endpoint. This design is studied in the context of a flexible model for the mean of the doseโ€“response. The design incorporates aspects of both __D__โ€ and __c__โ€optimality and can be used when the study goals u