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Comparative Study of the Possible Protective Effects of Cinnamic Acid and Cinnamaldehyde on Cisplatin-Induced Nephrotoxicity in Rats

✍ Scribed by El-Sayed, El-Sayed M.; Abd El-Raouf, Ola M.; Fawzy, Hala M.; Manie, Mohamed F.

Book ID
120984122
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
592 KB
Volume
27
Category
Article
ISSN
1095-6670

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Key words: nephrotoxicity; cisplatin; radical scavengers; methimazole; rat In adult rats 6 mg kg -1 body wt. cisplatin given i.p. was nephrotoxic. Four days of i.p. treatment with 40 mg kg -1 body wt. methimazole, which started 1 day before CP, prevented increases in blood urea nitrogen and in the r