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Comparative study of oxaprozin complexation with natural and chemically-modified cyclodextrins in solution and in the solid state

โœ Scribed by Francesca Maestrelli; Matteo Cecchi; Marzia Cirri; Gaetano Capasso; Natascia Mennini; Paola Mura


Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
480 KB
Volume
63
Category
Article
ISSN
0923-0750

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โœ V.R. Sinha; R. Anitha; S. Ghosh; A. Nanda; R. Kumria ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 310 KB

Inclusion complexation between celecoxib, a specific cyclooxygenase II inhibitor, and beta-cyclodextrin (b-CD) was studied in solution and solid state. Drug cyclodextrin complexes were prepared by spray drying while physical mixtures were obtained by simple blending. Inclusion complexes were charact