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Comparative study of human and rabbit cell infection with cell-free HTLV-I

✍ Scribed by Dr. Ichiro Yamade; Takahiro Isono; Tatsuya Ishiguro; Yoshinobu Yoshida

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 449 KB
Volume: 39
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890390114

No coin nor oath required. For personal study only.

✦ Synopsis

Infection of human and rabbit cells with cell-free HTLV-I was studied by PCR analysis. Both human and rabbit PBL were infected similarly by cellfree virus of both human and rabbit cell origin. Cells were infected with the cell-free virus without prior treatment and regardless of the concentration of the culture supernatant containing the virus. Human and rabbit cell lines were also infected similarly by the cell-free virus, the proviral DNA persisting for more than two months. The culture supernatants of HTLV-I-producing cells could thus be a potential cause of laboratory infections.

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