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Comparative studies of thyrotropin releasing hormone diazomethyl ketone and chloromethyl ketone analogs

✍ Scribed by James L. Balk; Robert B. Johnston; John T. Pelton


Book ID
118316032
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
432 KB
Volume
98
Category
Article
ISSN
0006-291X

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Tritium-labelled methyl farnesoate (PHI-MF, 6.6 Ci/mmol) was prepared from a tritiated allylic alcohol derivative by an efficient new one-pot halogen exchange-reductive dehalogenation sequence. The resulting [3H]-MF was converted in three steps to a diazomethyl ketone analog, ["HI-FDK, which can be