✦ LIBER ✦
An efficient synthesis of the crustacean hormone [12-3H]-methyl farnesoate and its photolabile analog [13-3H]-farnesyl diazomethyl ketone
✍ Scribed by István Ujváry; Glenn D. Prestwich
- Book ID
- 102372797
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 377 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Tritium-labelled methyl farnesoate (PHI-MF, 6.6 Ci/mmol) was prepared from a tritiated allylic alcohol derivative by an efficient new one-pot halogen exchange-reductive dehalogenation sequence. The resulting [3H]-MF was converted in three steps to a diazomethyl ketone analog, ["HI-FDK, which can be used for the photoaffinity labelling of MF binding proteins.