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Comparative QSAR and pharmacophore modeling of substituted 2-[2′-(dimethylamino) ethyl]-1, 2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones derivatives as anti-tumor activity

✍ Scribed by Mukesh C. Sharma, Smita Sharma, Pratibha Sharma…

Book ID
120908745
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
795 KB
Volume
22
Category
Article
ISSN
1054-2523

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ChemInform Abstract: 2-(2′-(Dimethylamino)ethyl)-1,2-dihydro-3H-dibenz(de,h)isoquinoline-1, 3-diones with Substituents at Positions 4, 8, 9, 10, and 11. Synthesis, Antitumor Activity, and Quantitative Structure-Activity Relationships.
✍ S. M. SAMI; R. T. DORR; D. S. ALBERTS; A. M. SOLYOM; W. A. REMERS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

2-(2'-(Dimethylamino)ethyl)-1,2-dihydro-3Hdibenz(de,h)isoquinoline-1, 3-diones with Substituents at Positions 4, 8, 9, 10, and 11. Synthesis, Antitumor Activity, and Quantitative Structure-Activity Relationships. -Twenty-four new title compounds are synthesized following standard routes as describe