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6- and 7-Substituted 2-[2‘-(Dimethylamino)ethyl]-1,2-dihydro-3 H - dibenz[ de , h ]isoquinoline-1,3-diones: Synthesis, Nucleophilic Displacements, Antitumor Activity, and Quantitative Structure−Activity Relationships

✍ Scribed by Sami, Salah M.; Dorr, Robert T.; Sólyom, Anikó M.; Alberts, David S.; Iyengar, Bhashyam S.; Remers, William A.

Book ID
126938952
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
250 KB
Volume
39
Category
Article
ISSN
0022-2623

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ChemInform Abstract: 2-(2′-(Dimethylamin
ChemInform Abstract: 2-(2′-(Dimethylamino)ethyl)-1,2-dihydro-3H-dibenz(de,h)isoquinoline-1, 3-diones with Substituents at Positions 4, 8, 9, 10, and 11. Synthesis, Antitumor Activity, and Quantitative Structure-Activity Relationships.
✍ S. M. SAMI; R. T. DORR; D. S. ALBERTS; A. M. SOLYOM; W. A. REMERS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

2-(2'-(Dimethylamino)ethyl)-1,2-dihydro-3Hdibenz(de,h)isoquinoline-1, 3-diones with Substituents at Positions 4, 8, 9, 10, and 11. Synthesis, Antitumor Activity, and Quantitative Structure-Activity Relationships. -Twenty-four new title compounds are synthesized following standard routes as describe