Chiral L-alpha-amino acids labeled with isotopic carbon can be conveniently prepared through the intermediacy of the cyclic peptide (diketopiperazine) derived from labeled glycine and an optically active L-alpha-amino acid such as L-valine IT. Kanmera, et al~, Tetrahedron Lett. 4483 (1979)]. After a
✦ LIBER ✦
Comparative pharmacokinetics of unlabeled and deuterium-labeled terbutaline: Demonstration of a small isotope effect
✍ Scribed by Lars Borgsträm; Claes Lindberg; Sven Jänsson; Klas Svensson
- Book ID
- 102404194
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 386 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3549
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Perdeuterated benzofluoranthenes have slightly shorter retention times than their equivalent unlabeled forms in a DB-5 capillary column. Under column overload conditions, perdeuterated benrofluoranthenes in moderate rnultifold excesses, which might be encountered in their use as internal standards a