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Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer

โœ Scribed by Miguel H. Bronchud; Jennifer M. Margison; Anthony Howell; Michael Lind; Samuel B. Lucas; Peter M. Wilkinson

Publisher
Springer
Year
1990
Tongue
English
Weight
472 KB
Volume
25
Category
Article
ISSN
0344-5704

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The chronopharmacokinetics of doxorubicin (DOX) has been studied in 18 patients suffering from breast cancer. They received combined chemotherapy including DOX (50 mg/m2 as an iv bolus), given at two different times (09.00 h or 21.00 h). The two randomized courses of the protocol were given to each

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