✦ LIBER ✦

Comparative Pharmacokinetics and Pharmacodynamics of Platelet Adenosine Diphosphate Receptor Antagonists and their Clinical Implications

✍ Scribed by Christopher N. Floyd, Gabriella Passacquale, Professor Albert Ferro

Book ID: 119931430
Publisher: Springer International Publishing AG
Year: 2012
Tongue: English
Weight: 222 KB
Volume: 51
Category: Article
ISSN: 0312-5963
DOI: 10.2165/11630740-000000000-00000

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The thienopyridine derivatives (platelet

The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments

✍ P. C. A. Kam; C. M. Nethery 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB

**Summary** The thienopyridines, ticlopidine and clopidogrel, are antiplatelet drugs. They are prodrugs and are metabolised in the liver to active metabolites that are non‐competitive antagonists of the platelet adenosine diphosphate receptor, P2Y~12~. Inhibition of platelet aggregation by these dru

Novel P2Y12 adenosine diphosphate recept

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): Pharmacodynamic and pharmacokinetic characterization

✍ Joseph M. Post; Serene Alexander; Yi-Xin Wang; Jon Vincelette; Ron Vergona; Lorr 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 946 KB

A response to ‘The thienopyridine deriva

A response to ‘The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments’, Kam PCA, Nethery CM, Anaesthesia 2003; 58: 28–35.

✍ R. Self 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB

ADENOSINE 5′-DIPHOSPHATE ANTAGONISTS AND

ADENOSINE 5′-DIPHOSPHATE ANTAGONISTS AND HUMAN PLATELETS: NO EVIDENCE THAT AGGREGATION AND INHIBITION OF STIMULATED ADENYLATE CYCLASE ARE MEDIATED BY DIFFERENT RECEPTORS

✍ N.J. CUSACK; S.M.O. HOURANI 📂 Article 📅 1982 🏛 Nature Publishing Group 🌐 English ⚖ 831 KB

Pharmacokinetics of sertindole and its m

Pharmacokinetics of sertindole and its metabolite dehydrosertindole in rats and characterization of their comparative pharmacodynamics based on in vivo D2 receptor occupancy and behavioural conditioned avoidance response

✍ Christoffer Bundgaard; Frank Larsen; Mads Kreilgaard; Lise T. Brennum; Christina 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB 👁 1 views

Pharmacokinetic and pharmacodynamic anal

Pharmacokinetic and pharmacodynamic analysis of TS-943, a selective non-peptide platelet glycoprotein-IIb/IIIa (GPIIb/IIIa) receptor antagonist, using a nonlinear mixed effect model in dogs

✍ A. Furuya; M. Nozawa; J. Gotoh; S. Jingu; M. Akimoto; S. Higuchi; T. Suwa; H. Og 📂 Article 📅 2002 🏛 Pharmaceutical Press 🌐 English ⚖ 237 KB