Comparative metabolism and kinetics of coumarin in mice and rats
β Scribed by S.L. Born; A.M. Api; R.A. Ford; F.R. Lefever; D.R. Hawkins
- Book ID
- 117450106
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 266 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0278-6915
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d e n quantitation of small sulfamethazine peaks impractical. The chloroform wash of the basic aqueous mixture seems to affect this component m a t . Overwashing at this point, however, causes a loss of sulfamethazine. Homogenizing or grinding the tissue prior to extraction tends to improve recover
Coumarin is widely used as a fragrance in cosmetics, perfumes and soaps. The Food and Drug Administration banned coumarin use in food because of reports that coumarin produced hepatotoxicity in rodents. Concerns about coumarin's safety have also been raised by toxicity testing conducted by the Natio