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Comparative Developmental Toxicity and Metabolism of Nitrazepam in Rats and Mice

✍ Scribed by S. Takeno; Y. Hirano; A. Kitamura; T. Sakai


Book ID
112265534
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
448 KB
Volume
121
Category
Article
ISSN
0041-008X

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## Abstract **BACKGROUND:** Emodin, a widely available herbal remedy, was evaluated for potential effects on pregnancy outcome. **METHODS:** Emodin was administered in feed to timed‐mated Sprague–Dawley (CD) rats (0, 425, 850, and 1700 ppm; gestational day [GD] 6–20), and Swiss Albino (CD‐1) mice (