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Comparative genomic hybridization as a tool to define two distinct chromosome 12-derived amplification units in well-differentiated liposarcomas

โœ Scribed by Ron F. Suijkerbuijk; Daniel E.M. Olde Weghuis; Margot Van Den Berg; Florence Pedeutour; Anne Forus; Ola Myklebost; Cliff Glier; Claude Turc-Carel; Ad Geurts van Kessel


Book ID
119106387
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
107 KB
Volume
77
Category
Article
ISSN
0165-4608

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Comparative genomic hybridization as a t
โœ Ron F. Suijkerbuijk; Daniel E. M. Olde Weghuis; Margot Van Den Berg; Ad Geurts V ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 379 KB

Well-differentiated liposarcomas (WDLPS) are frequently characterized by a near-diploid karyotype with supernumerary ring andlor giant rod-shaped marker chromosomes. We have shown, using fluorescence in situ hybridization (FISH) and molecular strategies, that these markers contain chromosome 12-deri