Comparative evaluation of different bacterial DNA-repair tests for rapid detection of chemical mutagens and carcinogens
โ Scribed by W. Suter; I. Jaeger
- Book ID
- 113250415
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 56 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0165-1161
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In more than thirty years of intensive research and development in the field of bacterial mutagenicity testing, a wide range of strains with various, genetic endpoints has become available for routine studies. Selective genetic systems of great simplicity and handiness have been developed which assa
## Abstract The feasibility of detection of carcinogenic chemicals using DNA repair synthesis of cultured human fibroblasts as measured by an unscheduled ^3^HTdR incorporation has been explored. Of 64 chemicals tested, 29 were proximate or ultimate carcinogens, 15 were precarcinogens that required