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A RAPID TECHNIQUE FOR THE QUANTITATION OF DNA-REPAIR SYNTHESIS IN THE HEPATOCYTE/DNA-REPAIR TEST FOR CHEMICAL CARCINOGENS

โœ Scribed by Felix R. Althaus; Henry C. Pitot

Book ID
118721100
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
177 KB
Volume
407
Category
Article
ISSN
0890-6564

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## Abstract The feasibility of detection of carcinogenic chemicals using DNA repair synthesis of cultured human fibroblasts as measured by an unscheduled ^3^HTdR incorporation has been explored. Of 64 chemicals tested, 29 were proximate or ultimate carcinogens, 15 were precarcinogens that required