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Comparative efficiency of sister-chromatid exchanges and chromosomal aberrations induced by chemical mutagens in vitro and in vivo

โœ Scribed by E.G. Shcheglova


Book ID
113251204
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
80 KB
Volume
147
Category
Article
ISSN
0165-1161

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Peripheral blood lymphocytes from three patients with Down syndrome (DS; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (SCEs). Cells in G0 were exposed to bleomycin (20-100 micrograms/ml) fo