Comparison of level of sister chromatid exchanges and chromosomal aberrations induced by chemical mutagensin vitro
β Scribed by E. G. Shcheglova; A. N. Chebotarev
- Publisher
- Springer US
- Year
- 1983
- Tongue
- English
- Weight
- 254 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0007-4888
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## Abstract The induction of chromosomal aberrations and sister chromatid exchange __in vivo__ in mouse spleen and bone marrow as well as __in vitro__ in cultured mouse spleen cells by the insecticide βCypermethrinβ (__cistrans__ 1:1) was investigated. The percentage of chromsomal aberrations in t
In vitro sister chromatid exchange (SCE) and chromosome aberration (ABS) tests have been extensively used to identify potential rodent carcinogens. A number of measures of potency were developed to describe in vitro SCE and ABS test results: the dose needed to induce a unit increase over the control