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Comparative effects of sodium channel blockers in short term rat whole embryo culture

✍ Scribed by Nilsson, Mats F; Sköld, Anna-Carin; Ericson, Ann-Christin; Annas, Anita; Villar, Rodrigo Palma; Cebers, Gvido; Hellmold, Heike; Gustafson, Anne-Lee; Webster, William S


Book ID
120609167
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
776 KB
Volume
272
Category
Article
ISSN
0041-008X

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Gestational day 11 rat embryos were cultured for 20 h in the presence of nifedipine (NIF), diltiazem (DIL) and verapamil (VER), and the effects of these calcium channel blockers on embryonic heart rate and gross morphology were examined. Reductions of embryonic heart rate were dose dependent and rev