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Suppressive Effects of Bay K 8644 on Toxicity of Calcium Channel Blockers in Cultured Rat Embryos

โœ Scribed by Yoshiki Ban; Toshio Nakatsuka; Hiroyoshi Matsumoto; Fumihiko Ikemoto; Takashi Makita


Book ID
115608722
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
306 KB
Volume
34
Category
Article
ISSN
0272-0590

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Effects of Calcium Channel Blockers on C
โœ Yoshiki Ban; Toshio Nakatsuka; Hiroyoshi Matsumoto ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 515 KB

Gestational day 11 rat embryos were cultured for 20 h in the presence of nifedipine (NIF), diltiazem (DIL) and verapamil (VER), and the effects of these calcium channel blockers on embryonic heart rate and gross morphology were examined. Reductions of embryonic heart rate were dose dependent and rev