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Comparative analysis of flow cytometry and polymerase chain reaction for the detection of minimal residual disease in childhood acute lymphoblastic leukemia

✍ Scribed by Neale, G A M; Coustan-Smith, E; Stow, P; Pan, Q; Chen, X; Pui, C-H; Campana, D


Book ID
110055874
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
116 KB
Volume
18
Category
Article
ISSN
0887-6924

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Patients with acute leukemia in clinical remission may still have up to 10 10 residual malignant cells (the upper limit of detection by standard morphologic techniques). Sensitive techniques to detect minimal residual disease (MRD) may allow better estimates of the leukemia burden and help the selec