Common variation in genes related to immune response and risk of childhood leukemia
β Scribed by Sohee Han; Hong Hoe Koo; Qing Lan; Kyoung-Mu Lee; Ae Kyung Park; Sue K. Park; Hyuna Sung; Hyo Seop Ahn; Hee Young Shin; Hyoung Jin Kang; Jong Jin Seo; Yoon-Ok Ahn; Ho Kim; Nathaniel Rothman; Daehee Kang
- Book ID
- 116533508
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 277 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0198-8859
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## Abstract Multiple myeloma (MM) is a Bβcell malignancy characterized by aberrant immune function. Using genomic DNA extracted from 127 MM cases aged 21β84 years and 545 populationβbased controls, we examined the risk of MM associated with 82 common variants in 45 genes that mediate immunity among