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Common variants at five new loci associated with early-onset inflammatory bowel disease

✍ Scribed by Imielinski, Marcin; Baldassano, Robert N; Griffiths, Anne; Russell, Richard K; Annese, Vito; Dubinsky, Marla; Kugathasan, Subra; Bradfield, Jonathan P; Walters, Thomas D; Sleiman, Patrick


Book ID
109914543
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
476 KB
Volume
41
Category
Article
ISSN
1061-4036

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Background: To date, a number of high-profile studies have yielded over 50 inflammatory bowel disease (IBD) disease genes/ loci. The polymorphisms rs9858542 (BSN) and rs3197999 (MST1), on 3p21 locus, have been found associated with susceptibility to IBD. We aimed to replicate these associations in a