Common skin cancers in porokeratosis
โ Scribed by E. Maubec; P. Duvillard; A. Margulis; B. Bachollet; G. Degois; M-F. Avril
- Book ID
- 108668207
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 211 KB
- Volume
- 152
- Category
- Article
- ISSN
- 0007-0963
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A 73-year-old man presented with typical lesions of disseminated superficial porokeratosis (DSP) and multiple seborrhoeic keratoses on his face, trunk and extremities, and later developed a keratoacanthoma on his lip. He belonged to a cancer-prone pedigree susceptible to colonic, uterine and other i
The p53 gene (TP53) is mutated in numerous human cancers. We have used it as a molecular target to characterize the induction of mutations in human skin cancers. About 50% of all skin cancers in normal individuals exhibit p53 mutations. This frequency rises to 90% in skin cancers of patients with th