Common polymorphism in p53 intron 2, IVS2+38G>C
β Scribed by Sigitas J. Verselis; Frederick P. Li
- Book ID
- 101344479
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 8 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1059-7794
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π SIMILAR VOLUMES
A p o l y m o r p h i s m in intron 2 of the p53 gene was identified by single-strand conformation polymorphism analysis. The result is a G-to-C transversion at bp +38 following the splice donor site of exon 2. ## PCR sequencing SSCP results of all individuals were confirmed by direct PCR sequenc
A polymorphism in intron 2 of the p53 gene, which gives rise to 2 alleles, A l and A2, was analyzed by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and direct DNA-sequencing techniques. The distribution of this allele in the peripheral blood in the Chinese population