✦ LIBER ✦

Common pharmaceuticals alter tissue proton NMR relaxation properties

✍ Scribed by Stephen J. Karlik

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 891 KB
Volume: 3
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910030202

No coin nor oath required. For personal study only.

✦ Synopsis

Differences in the tissue properties of water are the basis for the detailed anatomic visualization of internal body structures produced by NMR imaging. Physiological and pathological events have the potential to alter proton nuclear magnetic resonance relaxation properties through changes in water environment. In this study, the parenteral injection of pharmaceuticals produced significant changes (1 2-2 1%) in proton NMR relaxation times in tissues of treated rats. The extent of relaxation time change was both tissue specific and drug specific. Therefore, the effects of common pharmaceuticals should be considered in the interpretation of TIand T2-weighted NMR images.

📜 SIMILAR VOLUMES

Water proton NMR relaxation mechanisms i

Water proton NMR relaxation mechanisms in lung tissue

✍ M. Kveder; I. Zupančič; G. Lahajnar; R. Blinc; D. Šuput; D. C. Ailion; K. Ganesa 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 536 KB

The NMR relaxation times T i , T2, and TI were measured in isolated rat lungs as functions of external magnetic field Bo, temperature, and lung inflation. The observed linear dependence on Bo of the tissue-induced free induction decay rate (Tb)-' provides independent confirmation of the air/water in

Aldehyde fixative solutions alter the wa

Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue

✍ Timothy M. Shepherd; Peter E. Thelwall; Greg J. Stanisz; Stephen J. Blackband 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB

## Abstract Chemically‐fixed nervous tissues are well‐suited for high‐resolution, time‐intensive MRI acquisitions without motion artifacts, such as those required for brain atlas projects, but the aldehyde fixatives used may significantly alter tissue MRI properties. To test this hypothesis, this s

On the correlation between tissue hydrat

On the correlation between tissue hydration state and proton NMR relaxation rates in experimental liver transplantation

✍ Ewald Moser; Eduard Winklmayr; Martin Krassak 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB 👁 1 views

As the tissue hydration state is one of the most important parameters to predict viability cold stored livers before transplantation, we investigated the correlation between the tissue inverse total water fraction, reflecting the hydration state, and proton relaxation times in cold stored rat liver

Effect of induced field inhomogeneity on

Effect of induced field inhomogeneity on transverse proton NMR relaxation in tissue water and model systems

✍ Robert J. Kurland; Frank Q. H. Ngo 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 395 KB 👁 1 views

The effect of induced field inhomogeneity (IFI) on transverse NMR relaxation of water protons in tissue has been investigated by examining the field dependence of the effective transverse relaxation rates (1/T2 efF) for in vitro canine brain tissue samples. At fields of 0.47, 2.35, 7.05 T (correspon

In vivo magnetic resonance imaging of th

In vivo magnetic resonance imaging of the blue crab,Callinectes sapidus: Effect of cadmium accumulation in tissues on proton relaxation properties

✍ Brouwer, Marius ;Engel, David W. ;Bonaventura, Joseph ;Johnson, G. Allan 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 1014 KB

## Abstract Nuclear magnetic resonance imaging (MRI) has been used to visualize the internal anatomy of a living blue crab. The resolution obtained in these studies was sufficient to distinguish individual organs by the differences in their proton densities and proton relaxation properties. T~1~ (s