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Common human Toll-like receptor 9 polymorphisms and haplotypes: association with atopy and functional relevance

✍ Scribed by B. Berghöfer; T. Frommer; I. R. König; A. Ziegler; T. Chakraborty; G. Bein; H. Hackstein

Book ID
108687572
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
160 KB
Volume
35
Category
Article
ISSN
0954-7894

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## Abstract ## Background Toll-like receptor (TLR) 9 is the pattern recognition receptor for microbial DNA. Genetic variation within pattern recognition receptors for bacterial endotoxin and exotoxin has been shown to be associated with the risk of sepsis and organ dysfunction in critical illness.