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Polymorphisms in the toll-like receptor 9 gene associated with sepsis and multiple organ dysfunction after major blunt trauma (Br J Surg 2011; 98: 1252–1259)

✍ Scribed by P. Zhao; G. Lu; L. Cai

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 67 KB
Volume: 99
Category: Article
ISSN: 0007-1323
DOI: 10.1002/bjs.7828

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✍ J.-X. Jiang 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 67 KB

Polymorphisms in the toll-like receptor

Polymorphisms in the toll-like receptor 9 gene associated with sepsis and multiple organ dysfunction after major blunt trauma

✍ K.-H. Chen; L. Zeng; W. Gu; J. Zhou; D.-Y. Du; J.-X. Jiang 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 464 KB

## Abstract ## Background Toll-like receptor (TLR) 9 is the pattern recognition receptor for microbial DNA. Genetic variation within pattern recognition receptors for bacterial endotoxin and exotoxin has been shown to be associated with the risk of sepsis and organ dysfunction in critical illness.