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Commercial Synthesis of Nitrazepam via the Interaction of 2-Chloro-5-nitrobenzophenone with Ethylene Diamine.

✍ Scribed by V. N. Anikeev; A. I. Petrunin; Y. N. Zhukov; M. T. Kilin; F. V. Guss


Book ID
101983906
Publisher
John Wiley and Sons
Year
2006
Weight
14 KB
Volume
37
Category
Article
ISSN
0931-7597

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Synthesis of [2H13]heptanoic acid via th
✍ Hirohisa Tsuzuki; Mamoru Mukumoto; Takehito Tsukinoki; Shuntaro Mataka; Masashi 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 222 KB

## Abstract [^2^H~13~]Heptanoic acid was synthesized as its methyl ester (4) (deuterium content: 96%) with Ni‐Al alloy in 10% NaOD‐D~2~O __via__ the desulfurization of methyl 3‐chloro‐5,6‐dibromothieno[3,2,__b__]thiophene‐2‐carboxylate (3), which was derived from 4,5‐dibromothiophene‐2‐carboaldehyd