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Comments on “compartmental biodistribution of a monoclonal antibody against human lung adenocarcinoma grown in athymic mice”

✍ Scribed by Rescigno, Aldo; Brill, A.Bertrand; Bushe, Harry; Hnatowich, Don.J

Book ID
122462444
Publisher
Elsevier Science
Year
1991
Weight
89 KB
Volume
18
Category
Article
ISSN
0883-2897

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Biodistribution of a monoclonal antibody
Biodistribution of a monoclonal antibody (RNL-1) against the neural cell adhesion molecule (NCAM) in athymic mice bearing human small-cell lung-cancer xenografts
✍ O. C. Boerman; E. P. Mijnheere; J. L. V. Broers; G. P. Vooijs; F. C. S. Ramaeker 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 795 KB

The purpose of this investigation was to determine the targeting potential of the murine monoclonal antibody (MAb) RNL-I for human small-cell lung cancer (SCLC) in a nude mouse model. RNL-I is preferentially reactive with SCLC and lung carcinoids, and was classified as a cluster-I MAb as defined by